Package: PPMR
Title: Probabilistic Two Sample Mendelian Randomization
Type: Package
Version: 1.0.1
Authors@R: c(
    person(given = "Zhongshang", family = "Yuan", role = c("aut")),
    person(given = "Xiang", family = "Zhou", role = c("aut"), email = "xzhousph@umich.edu"),
    person(given = "Michael", family = "Kleinsasser", role = c("cre"), email = "mkleinsa@umich.edu"))
Description: Efficient statistical inference of two-sample MR (Mendelian Randomization) analysis. 
    It can account for the correlated instruments and the horizontal pleiotropy, 
    and can provide the accurate estimates of both causal effect and horizontal 
    pleiotropy effect as well as the two corresponding p-values. There are two main 
    functions in the 'PPMR' package. One is PMR_individual() for individual level data, 
    the other is PMR_summary() for summary data.
License: GPL-3
Encoding: UTF-8
LazyData: true
Imports: Rcpp (>= 1.0.0)
LinkingTo: Rcpp, RcppArmadillo
RoxygenNote: 7.3.2
NeedsCompilation: yes
BugReports: https://github.com/umich-biostatistics/PPMR/issues
Packaged: 2025-09-17 19:02:37 UTC; mk
Author: Zhongshang Yuan [aut],
  Xiang Zhou [aut],
  Michael Kleinsasser [cre]
Maintainer: Michael Kleinsasser <mkleinsa@umich.edu>
Depends: R (>= 3.5.0)
Repository: CRAN
Date/Publication: 2025-09-17 19:20:09 UTC
Built: R 4.6.0; x86_64-apple-darwin20; 2026-04-27 00:24:59 UTC; unix
Archs: PPMR.so.dSYM
