GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Version:	1.2
Published:	2016-09-12
DOI:	10.32614/CRAN.package.GWsignif
Author:	ChangJiang Xu and Celia M.T. Greenwood
Maintainer:	ChangJiang Xu <changjiang.h.xu at gmail.com>
License:	GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation:	no
CRAN checks:	GWsignif results

Documentation:

Reference manual:

GWsignif.pdf

Downloads:

Package source:	GWsignif_1.2.tar.gz
Windows binaries:	r-devel: GWsignif_1.2.zip, r-release: GWsignif_1.2.zip, r-oldrel: GWsignif_1.2.zip
macOS binaries:	r-devel (arm64): GWsignif_1.2.tgz, r-release (arm64): GWsignif_1.2.tgz, r-oldrel (arm64): GWsignif_1.2.tgz, r-devel (x86_64): GWsignif_1.2.tgz, r-release (x86_64): GWsignif_1.2.tgz, r-oldrel (x86_64): GWsignif_1.2.tgz
Old sources:	GWsignif archive

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