TestREnlme: Nonparametric Tests for Random Effects in Linear and Nonlinear Mixed-Effects Models

Provides nonparametric permutation tests for testing all or any subset of random effects in linear and nonlinear mixed-effects models, without requiring normality or other distributional assumptions on random effects or errors. Three distribution-free variance-component estimators are implemented: Variance Least Squares ('VLS'), Method of Moments ('MM'), and Method of Moments with First-Order Approximation ('MMF'). A permutation procedure is used to obtain finite-sample p-values. Plotting functions support data exploration, model evaluation, and communication of results. Methods are described in Uwimpuhwe, Drikvandi, and Blozis (2026) <doi:10.1002/sim.70605>.

Version: 0.1.0
Depends: R (≥ 4.1.0)
Imports: nlme (≥ 3.1-150), Matrix (≥ 1.3-0), MASS (≥ 7.3-54), mgsub (≥ 1.7.3), matrixcalc (≥ 1.0-5), nls.multstart (≥ 2.0.0), ggplot2 (≥ 3.3.5), expm (≥ 0.999-6), withr (≥ 3.0.2), stats, utils, rlang
Suggests: knitr, rmarkdown, ggpubr (≥ 0.4.0), testthat (≥ 3.0.0), reshape2 (≥ 1.4.4)
Published: 2026-07-03
DOI: 10.32614/CRAN.package.TestREnlme (may not be active yet)
Author: Germaine Uwimpuhwe [aut, cre], Reza Drikvandi [aut], Shelley A. Blozis [aut]
Maintainer: Germaine Uwimpuhwe <germaine.uwimpuhwe at durham.ac.uk>
BugReports: https://github.com/germaine86/TestREnlme/issues
License: GPL (≥ 3)
URL: https://github.com/germaine86/TestREnlme
NeedsCompilation: no
CRAN checks: TestREnlme results

Documentation:

Reference manual: TestREnlme.html , TestREnlme.pdf
Vignettes: TestREnlme (source, R code)

Downloads:

Package source: TestREnlme_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): TestREnlme_0.1.0.tgz, r-oldrel (arm64): TestREnlme_0.1.0.tgz, r-release (x86_64): not available, r-oldrel (x86_64): TestREnlme_0.1.0.tgz

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