hierNest: Penalized Regression with Hierarchical Nested Parameterization Structure

Efficient implementation of penalized regression with hierarchical nested parametrization for grouped data. The package provides penalized regression methods that decompose subgroup specific effects into shared global effects, Major subgroup specific effects, and Minor subgroup specific effects, enabling structured borrowing of information across related clinical subgroups. Both lasso and hierarchical overlapping group lasso penalties are supported to encourage sparsity while respecting the nested subgroup structure. Efficient computation is achieved through a modified design matrix representation and a custom majorization minimization algorithm for overlapping group penalties.

Version: 1.0.0
Depends: R (≥ 3.5)
Imports: cli, dotCall64, ggplot2, magrittr, Matrix, methods, rlang, RSpectra, tidyr, rTensor, pROC, plotly
Suggests: dplyr, gglasso, glmnet, knitr, markdown, rmarkdown, splines, testthat (≥ 3.0.0)
Published: 2026-03-24
DOI: 10.32614/CRAN.package.hierNest (may not be active yet)
Author: Ziren Jiang [aut, cre], Jared Huling [aut], Jue Hou [aut], Lingfeng Huo [aut], Daniel J. McDonald [ctb], Xiaoxuan Liang [ctb], Anibal Solón Heinsfeld [ctb], Aaron Cohen [ctb], Yi Yang [ctb], Hui Zou [ctb], Jerome Friedman [ctb], Trevor Hastie [ctb], Rob Tibshirani [ctb], Balasubramanian Narasimhan [ctb], Kenneth Tay [ctb], Noah Simon [ctb], Junyang Qian [ctb], James Yang [ctb]
Maintainer: Ziren Jiang <jian0746 at umn.edu>
BugReports: https://github.com/ZirenJiang/hierNest/issues
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
URL: https://github.com/ZirenJiang/hierNest
NeedsCompilation: yes
Materials: README
CRAN checks: hierNest results [issues need fixing before 2026-04-07]

Documentation:

Reference manual: hierNest.html , hierNest.pdf
Vignettes: Getting Started with hierNest (source, R code)

Downloads:

Package source: hierNest_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): hierNest_1.0.0.tgz, r-oldrel (arm64): not available, r-release (x86_64): hierNest_1.0.0.tgz, r-oldrel (x86_64): hierNest_1.0.0.tgz

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