valytics: Statistical Methods for Analytical Method Comparison and Validation

Provides statistical methods for analytical method comparison and validation studies. Implements Bland-Altman analysis for assessing agreement between measurement methods (Bland & Altman (1986) <doi:10.1016/S0140-6736(86)90837-8>), Passing-Bablok regression for non-parametric method comparison (Passing & Bablok (1983) <doi:10.1515/cclm.1983.21.11.709>), and Deming regression accounting for measurement error in both variables (Linnet (1993) <doi:10.1093/clinchem/39.3.424>). Also includes tools for setting quality goals based on biological variation (Fraser & Petersen (1993) <doi:10.1093/clinchem/39.7.1447>) and calculating Six Sigma metrics. Commonly used in clinical laboratory method validation. Provides publication-ready plots and comprehensive statistical summaries.

Version: 0.3.0
Depends: R (≥ 3.5.0)
Imports: ggplot2, robslopes
Suggests: testthat (≥ 3.0.0), knitr (≥ 1.43), rmarkdown (≥ 2.22)
Published: 2026-01-22
DOI: 10.32614/CRAN.package.valytics (may not be active yet)
Author: Marcello Grassi ORCID iD [aut, cre]
Maintainer: Marcello Grassi <marcello.grassi at tum.de>
BugReports: https://github.com/marcellogr/valytics/issues
License: GPL-3
URL: https://github.com/marcellogr/valytics
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: valytics results

Documentation:

Reference manual: valytics.html , valytics.pdf
Vignettes: Deming Regression for Method Comparison (source, R code)
Method Comparison Workflow (source, R code)
Setting Quality Goals with Biological Variation (source, R code)
Understanding Method Comparison Statistics (source, R code)

Downloads:

Package source: valytics_0.3.0.tar.gz
Windows binaries: r-devel: not available, r-release: valytics_0.3.0.zip, r-oldrel: valytics_0.3.0.zip
macOS binaries: r-release (arm64): valytics_0.3.0.tgz, r-oldrel (arm64): valytics_0.3.0.tgz, r-release (x86_64): valytics_0.3.0.tgz, r-oldrel (x86_64): valytics_0.3.0.tgz

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